임상 발전.
A. 임상개발에 가장 적합한 복방(S)을 선택합니다. B. 인체의 안전성, 유효성 및 선택성을 평가하기 위해 I기, II기 및 III기 임상시험을 실시한다. C. 규제 부서의 승인을 받았다.
화학 원료를 구입해야하는 경우 요청 정보를 제출하여최신견적을받으십시오.
임상 발전.의 학술 논문
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Design of potent and selective antagonists of the vasopressor responses to arginine-vasopressin
화학 물질
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3-MERCAPTO-3-METHYL-BUTYRYL-TYR-PHE-VAL-ASN-CYS-PRO-D-ARG-GLY-NH2
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Identification of novel isocytosine derivatives as xanthine oxidase inhibitors from a set of virtual screening hits
화학 물질
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N-(2-amino-6-(4-methoxyphenyl)pyrimidin-4-yl)methanesulfonamide
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Discovery of a novel small molecule agonist scaffold for the APJ receptor
화학 물질
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(2S)-cyclohexyl({[5-(2,6-dimethoxyphenyl)-1-(4-fluorophenyl)-1H-pyrazol-3-yl]carbonyl}amino)ethanoic acid
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Structure-based design of 5-Methylpyrimidopyridone derivatives as new wild-type sparing inhibitors of the epidermal growth factor receptor triple mutant (EGFRL858R/T790M/C797S)
화학 물질
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tert-butyl (S)-3-((5-bromo-2-chloropyrimidin-4-yl)amino)piperidine-1-carboxylate
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bis(benzonitrile)palladium(II) dichloride
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Lead optimization of isocytosine-derived xanthine oxidase inhibitors
화학 물질
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C16H18N4O2
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Identification of a series of highly potent activators of the Nurr1 signaling pathway
화학 물질
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4-[(2-메톡시에톡시)메틸]벤조산
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Synthesis and structure-activity relationship study of antidiabetic penta-O-galloyl-D-glucopyranose and its analogues
화학 물질
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1,2,3,4-tetrakis-O-(3,4,5-trihydroxybenzoyl)-alpha-D-glucopyranose
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CCR5 receptor antagonists: Discovery and SAR of novel 4-hydroxypiperidine derivatives
화학 물질
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5-BROMO-2-[(4-클로로벤질)옥시]벤잘데하이드
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Identification and SAR of squarate inhibitors of mitogen activated protein kinase-activated protein kinase 2 (MK-2)
화학 물질
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3-{[(1S)-1-phenylethyl]amino}-4-(pyridin-4-ylamino)cyclobut-3-ene-1,2-dione
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5-HT6 receptor antagonists: lead optimisation and biological evaluation of N-aryl and N-heteroaryl 4-amino-benzene sulfonamides
화학 물질
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N-[4-(6-chloro-2-isopropylamino-pyrimidin-4-ylsulfamoyl)-phenyl]-acetamide
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Novel cyclohexyl-amides as potent antibacterials targeting bacterial type IIA topoisomerases
화학 물질
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methyl (1α,3α,4β)-4-[(tert-butoxycarbonyl)amino]-3-hydroxycyclohexanecarboxylate
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Synthesis and biological evaluation of quinazoline derivatives – A SAR study of novel inhibitors of ABCG2
화학 물질
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4-phenoxy-2-phenylquinazoline
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Development of a potent and selective FLT3 kinase inhibitor by systematic expansion of a non-selective fragment-screening hit
화학 물질
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1H-Indazole-3-carboxamide, N-(2-methylphenyl)-
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Rational discovery of a highly novel and selective mTOR inhibitor
화학 물질
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1-cyclopropyl-3-(4-(5-(2,2-difluoropropyl)-6a-methyl-6-oxo-5,6,6a,7,9,10-hexahydro[1,4]oxazino[3,4-h]pteridin-2-yl)phenyl)urea
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Development of Kinase Inactive PD173955 Analogues for Reducing Production of Aβ Peptides
화학 물질
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6-(2,6-DICHLOROPHENYL)-8-METHYL-2-METHYLSULFONYL-8H-PYRIDO[2,3-D]PYRIMIDIN-7-ONE
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Synthesis and biological evaluation of new disubstituted analogues of 6-methoxy-3-(3′,4′,5′-trimethoxybenzoyl)-1H-indole (BPR0L075), as potential antivascular agents
화학 물질
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N-phenylsulfonyl-5-hydroxy-6-methoxy-1H-indole
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Investigation of subsite preferences in aminopeptidase A (EC 3.4.11.7) led to the design of the first highly potent and selective inhibitors of this enzyme
화학 물질
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(2S,3S), 2-[4-methoxybenzylsulfanyl], 3-tertiobutyloxycarbonylamino-hexane-dioic acid 1-allyl ester, 6-tertiobutyl ester
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trifluoroacetic acid
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Synthesis and Phosphodiesterase Activity of Carboxylic Acid Mimetics of Cyclic Guanosine 3',5'-Monophosphate
화학 물질
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2H- 시클로 펜타 [b] 푸란 -2- 카르보니 트릴, 5- (아세틸 옥시) 헥사 히드로-(9Cl)
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