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SAR(구조적 관계)
노이즈 방향족 측면 체인과 그 특정 대체 베이스의 선택은 항균 성능에 영향을 줍니다.연구진은 항균 활성과 선택성을 강화하기 위해 다양한 구조 손질을 탐색했다.
화학 원료를 구입해야하는 경우 요청 정보를 제출하여최신견적을받으십시오.
SAR(구조적 관계)의 학술 논문
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Synthesis and Antibacterial Activities of 4-Pyrrolidinylthio Carbapenems: Containing Heteroaromatics as a Side Chain
화학 물질
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(4R,5S,6S)-3-((3S,5S)-1-Allyloxycarbonyl-5-imidazol-1-ylmethyl-pyrrolidin-3-ylsulfanyl)-6-((R)-1-hydroxy-ethyl)-4-methyl-7-oxo-1-aza-bicyclo[3.2.0]hept-2-ene-2-carboxylic acid allyl ester
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Synthesis, properties, and pharmacokinetic studies of N2-phenylguanine derivatives as inhibitors of herpes simplex virus thymidine kinases
화학 물질
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6H-Purin-6-one, 1,9-dihydro-9-(4-hydroxybutyl)-2-(phenylamino)-
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2- 브로 모 히폭 산틴
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Synthesis and antifungal activity of substituted-10-methyl-1,2,3,4- tetrahydropyrazino[1,2-a]indoles
화학 물질
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Pyrazino[1,2-a]indole, 1,2,3,4-tetrahydro-10-methyl-1-phenyl-
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Structure-activity, theoretical, and X-ray studies on the intramolecular interactions in a series of novel histamine H2 receptor antagonists
화학 물질
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2-[[3-(N,N-Dimethylaminomethyl)phenyl]methylthio]ethanamine
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Synthesis and Evaluation of Non-peptidic Cysteine Protease Inhibitors of P. falciparum Derived from Etacrynic Acid
화학 물질
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6-{2-[2,3-dichloro-4-(2-methylenebutyryl)phenoxy]acetylamino}hexanoic acid
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Tariquidar-related triazoles as potent, selective and stable inhibitors of ABCG2 (BCRP)
화학 물질
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1-(2-아미노-4-브로모페닐)에타논
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TVB-2640
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훽스트 33342
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Hydrazine derivatives and o-benzoylbenzoic acid as a source of phthalazines with their antimicrobial activities
화학 물질
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1(2H)-Phthalazinethione, 2,4-diphenyl-
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Benzylamine Antioxidants: Relationship between Structure, Peroxyl Radical Scavenging, Lipid Peroxidation Inhibition, and Cytoprotection
화학 물질
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4-[(butylamino)methyl]-2,6-dimethoxyphenol
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Identification of 4-anilino-6-aminoquinazoline derivatives as potential MERS-CoV inhibitors
화학 물질
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6-아미노-4-(3-클로로-4-플루오로아닐리노)퀴나졸린
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가솔린
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Synthesis and cytotoxic evaluation of a series of γ-substituted γ-aryloxymethyl-α-methylene-γ-butyrolactones against cancer cells
화학 물질
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1-(4-fluorophenyl)-2-(2-naphthyloxy)ethanone
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Synthesis and SAR of 6-substituted purine derivatives as novel selective positive inotropes
화학 물질
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1-(1-chloro-2-hydroxy-3-propanyl)-4-[bis(4-fluorophenyl)-methyl]-piperazine
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1,3,4-Oxadiazole-3(2H)-carboxamide derivatives as potential novel class of monoamine oxidase (MAO) inhibitors: Synthesis, evaluation, and role of urea moiety
화학 물질
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5-(benzo[d][1,3]dioxol-5-yl)-2,2-dibutyl-N-(2-chlorobenzoyl)-1,3,4-oxadiazole-3(2H)-carboxamide
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Synthesis and evaluation of
aseries of homologues of lobelane at the vesicular monoamine transporter-2화학 물질
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2-phenyl-6-(3-phenylpropyl)pyridine
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CCR5 receptor antagonists: Discovery and SAR of novel 4-hydroxypiperidine derivatives
화학 물질
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5-BROMO-2-[(4-클로로벤질)옥시]벤잘데하이드
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Synthesis and antimalarial activity of 2-guanidino-4-oxoimidazoline derivatives
화학 물질
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N-(3,4-dichlorophenyl)-N'-(1-methyl-4-oxo-4,5-dihydro-1H-imidazol-2-yl)guanidine
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Synthesis and pharmacological screening of several aroyl and heteroaroyl selenylacetic acid derivatives as cytotoxic and antiproliferative agents
화학 물질
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(4-tert-butylbenzoylselenyl)acetic acid
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Structure-activity relationship-guided development of retinoic acid receptor-related orphan receptor gamma (RORγ)-selective inverse agonists with a phenanthridin-6(5H)-one skeleton from a liver X receptor ligand
화학 물질
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2-(4-butylamino-3-methoxyphenyl)-1,1,1,3,3,3-hexafluoropropan-2-ol
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Synthesis and evaluation of 2′,4′,6′-trihydroxychalcones as a new class of tyrosinase inhibitors
화학 물질
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4H-1-Benzopyran-4-one, 2-(2,4-dihydroxyphenyl)-2,3-dihydro-5,7-dihydroxy-
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A matrix-focused structure-activity and binding site flexibility study of quinolinol inhibitors of botulinum neurotoxin serotype A
화학 물질
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7-[(2-FLUOROPHENYL)(PYRIDIN-2-YLAMINO)METHYL]QUINOLIN-8-OL
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Synthesis and cytotoxicity studies of novel [1,2,4] Triazolo [1,5-a]pyrimidine-7-amines
화학 물질
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N-(3-chlorophenyl)-5-methyl-2-(3-((5-(morpholinomethyl)furan-2-yl)methylthio)propyl)-[1,2,4]triazolo[1,5-a]pyrimidin-7-amine
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TVB-2640
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Synthesis and Antiviral Activity of Phosphonoacetic and Phosphonoformic Acid Esters of 5-Bromo-2'-deoxyuridine and Related Pyrimidine Nucleosides and Acyclonucleosides
화학 물질
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Sodium; {[(2R,3S,5R)-5-(2,4-dioxo-5-vinyl-3,4-dihydro-2H-pyrimidin-1-yl)-3-hydroxy-tetrahydro-furan-2-ylmethoxy]-hydroxy-phosphoryl}-acetate
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Synthesis and biological evaluation of penam sulfones as inhibitors of β-lactamases
화학 물질
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benzhydryl 2β-(chloroacetoxy)methyl-1,1-dioxo-penicillanate
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Synthesis and antifungal activity of some new quinazoline and benzoxazinone derivatives
화학 물질
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3,5-dibromo-2-isobutyrylaminobenzoyl-hydrazine
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Substituted tetrahydroisoquinolines: synthesis, characterization, antitumor activity and other biological properties
화학 물질
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2-(2,3-DIHYDRO-1,4-BENZODIOXIN-6-YL)에타나민 염산염
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2,6-Disubstituted imidazo[2,1-b][1,3,4]thiadiazoles: Search for anticancer agents
화학 물질
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2-(2-fluorobiphenyl-4-yl)-6-phenylimidazo[2,1-b][1,3,4]thiadiazole
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Design and synthesis of a novel class of thrombin inhibitors incorporating heterocyclic dipeptide surrogates
화학 물질
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2-methyl-5-benzylsulfonylamino-6-oxo-1 6-dihydro-1-pyrimidinylacetic acid
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Development of Small Molecules with a Noncanonical Binding Mode to HIV-1 Trans Activation Response (TAR) RNA
화학 물질
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3-amino-6-methyl-N-(3-(trifluoromethyl)phenyl)thieno[2,3-b]pyridine-2-carboxamide
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Pyrazolo[1,5-a]pyrimidine-based inhibitors of HCV polymerase
화학 물질
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C23H27NO2S
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Novel indole-based peroxisome proliferator-activated receptor agonists: Design, SAR, structural biology, and biological activities
화학 물질
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2-[4-(allyloxy)-2-hydroxyphenyl]-1-phenyl-1-ethanone
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Further explorations on bridged 1,2,4-trioxanes
화학 물질
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5-[5-(tert-butyl-dimethyl-silanyloxy)-pentane-1-sulfonyl]-1-phenyl-1H-tetrazole
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Studies on the Insecticidal Activities of Some New N-Benzoyl-N'-Arylureas
화학 물질
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(4- 아미노 페닐) (4- 플루오로 페닐) 메탄 온
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Approaches to the high-throughput synthesis of analogues of dihydroaertiginoic acid
화학 물질
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L-Cysteine, N-(2-hydroxybenzoyl)-
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Synthesis of piplartine analogs and preliminary findings on structure–antimicrobial activity relationship
화학 물질
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(E)-N′-cinnamoylbenzohydrazide
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Studies on coumarins, II
화학 물질
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6-Methyl-4-phenoxymethyl-chromen-2-one
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Small-molecular, non-peptide, non-ATP-competitive polo-like kinase 1 (Plk1) inhibitors with a terphenyl skeleton
화학 물질
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3,5-Difluoro-4-hydroxybenzeneboronic acid pinacol ester, 96%
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Design of cell-permeable stapled peptides as HIV-1 integrase inhibitors
화학 물질
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C75H112N18O13
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Discovery of novel isothiazole inhibitors of the TrkA kinase: Structure-activity relationship, computer modeling, optimization, and identification of highly potent antagonists
화학 물질
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(4-cyano-3-mercapto-isothiazol-5-yl)-carbamic acid phenyl ester
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Design synthesis and antibacterial activity studies of new thiadiazoloquinolone compounds
화학 물질
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ethyl 2-[(2,4-dichloro-5-fluoro-3-nitrophenyl)carbonyl]-3-(dimethylamino)prop-2-enoate
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"Vinylogs" and "acetylenylogs" of β-adrenergic agents
화학 물질
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2-<2'-(trifluoromethyl)phenyl>ethen-1-yl-oxirane
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