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Product Details
23239-88-5 Name |
|
Name |
Benzocaine hydrochloride |
Synonym |
Benzocaine hydrochl;Benzoic acid, 4-aMino-,ethyl ester, hydrochloride (1:1);ETHYL 4-AMINOBENZOATE HYDROCHLORIDE;BENZOCAINE HCL;BENZOCAINE HYDROCHLORIDE;Benzocaine hydrochloride(Cas number23239-88-5);Ethyl p-aminobenzoate hydrochloride;benzocaina benzocane powder |
23239-88-5 Chemical & Physical Properties |
|
Melting point |
208ºC |
Boiling point |
495ºC at 760mmHg |
Density |
1.286g/cm3 |
Molecular Formula |
C9H12ClNO2 |
Molecular Weight |
201.650 |
Flash Point |
228.6ºC |
PSA |
52.32000 |
LogP |
2.82870 |
Exact Mass |
201.055649 |
Vapour Pressure |
0.000589mmHg at 25°C |
storage temp. |
Inert atmosphere,Room Temperature |
23239-88-5 Description |
Benzocaine is a local anesthetic drug. It is directly applied to the skin and used as a topical pain reliever or in cough drops. Benzocaine works by creating a chemical barrier that halts the build up of sodium, which accumulates as the nerve endings are stimulated by pain. When sodium builds up, electrical signals also build in the nerve ending and are transmitted to the brain, which interprets the signals as pain. Benzocaine hydrochloride is a salt modification of benzocaine, formed when benzocaine is complexed with hydrochloric acid. Compared to benzocaine, benzocaine hydrochloride is more water soluble, making it more appropriate for oral administration. Benzocaine hydrochloride is usually made into powder or oil paste and used to heal wounds, ulcers, burns, skin abrasion, and hemorrhoids. Through the reduction in the excretion of ammonia and carbon dioxide of fish by benzocaine hydrochloride, the pH and alkalinity values of the transport water remains constant, thereby, benzocaine hydrochloride is used as an aid in the transport of fish. |
23239-88-5 Uses |
Benzocaine Hydrochloride can be used as promising MAO inhibitors. |
A compound represented by the formula (1): wherein each symbol is as defined in the specification, and a salt thereof and a prodrug thereof unexpectedly have superior GPR40 receptor agonist activity, superior in the properties as a pharmaceutical product such as stability and the like, and can be a safe and useful pharmaceutical agent as a drug for the prophylaxis or treatment of GPR40 receptor related pathology or diseases such as diabetes and the like.
In this paper, we report the synthesis and aggregation properties of new self-complementary organic molecules containing guanidinium and carboxylate groups. The crystal structures of the guanidinium carboxylates showed linear bidentate hydrogen bonding between the guanidinium and the carboxylate groups.
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